Phenothiazine dye-loaded chitosan cryogels as multifunctional antibacterial wound dressings
Reem Ghonaim, Bahaa A. Hemdan, Hesham R. El-Seedi, Mohamed M. A. Badr, Tarek S. Aysha, Mervat S. El-Sedik, Samar A. El-Kholy, Mehrez E. El-Naggar · 2026
Read Phenothiazine dye-loaded chitosan cryogels as multifunctional antibacterial wound dressings by Reem Ghonaim, Bahaa A. Hemdan, Hesham R. El-Seedi, Mohamed M. A. Badr, Tarek S. Aysha, Mervat S. El-Sedik, Samar A. El-Kholy, Mehrez E. El-Naggar (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13284323.txt.
Description
Reem Ghonaim and co-authors report a laboratory study, published in 2026, on wound dressings made from chitosan cryogels loaded with a phenothiazine dye. The team made a chalcone form of the dye and mixed it into sponge-like chitosan gels. They then tested how well the gels killed bacteria linked to wound infection.
Growth tests, leakage assays, and a Microtox test showed strong killing of six bacterial species, with clear zones near 33 mm for Escherichia coli in the best gels. The gels also showed good heat stability and no harmful effects in the safety test. Docking work pointed to binding with CDK6 and CDK2 proteins. The authors present the gels as low-cost, multi-use dressings that could help infected wounds heal.
Catalog record
| CREATOR | Reem Ghonaim, Bahaa A. Hemdan, Hesham R. El-Seedi, Mohamed M. A. Badr, Tarek S. Aysha, Mervat S. El-Sedik, Samar A. El-Kholy, Mehrez E. El-Naggar |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60891 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |