A novel collagen hydrogel loaded with primary brown sugar for accelerating burn wound healing by a synergistic mechanism
Ziying Guan, Liren Wei, Liaoyuan Han, Jian Lu, Yanfei Tan, Qingrong Wei · 2026
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Description
Ziying Guan and co-authors created a wound gel in 2026 that pairs collagen with brown sugar for burn care. Brown sugar, the first extract from sugarcane, has a long history in Chinese traditional medicine. The gel also carried epicatechin, a plant compound, and the team checked whether the parts worked better together than apart.
In lab tests the gel killed Staphylococcus aureus, a common wound germ, and mopped up harmful free radicals. It lowered an inflammatory signal, raised a calming one, and sped skin cell movement and growth. In mouse and rat burn models, treated wounds closed far faster, with about six percent of the wound left at day fourteen. New tissue laid down more ordered collagen and roughly twice the new blood vessels of controls.
Catalog record
| CREATOR | Ziying Guan, Liren Wei, Liaoyuan Han, Jian Lu, Yanfei Tan, Qingrong Wei |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |