External validation of the VALE scoring system for hemorrhage risk in pediatric AVM patients
Sepide Kashefiolasl, Luciana Porto, Karsten Lachner, Michael Merker, Roland Schrewe, Susanne Schubert-Bast, Fee Keil, Vincent Prinz, Tobias Finger, Marcus Czabanka · 2026
Read External validation of the VALE scoring system for hemorrhage risk in pediatric AVM patients by Sepide Kashefiolasl, Luciana Porto, Karsten Lachner, Michael Merker, Roland Schrewe, Susanne Schubert-Bast, Fee Keil, Vincent Prinz, Tobias Finger, Marcus Czabanka (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13283164.txt.
Description
An adult bleeding-risk score for brain vessel tangles falters in children, Frankfurt records analyzed by Sepide Kashefiolasl show in 2026. Such tangles are a top cause of brain bleeding in young patients. The VALE score was built for adults, so its value in children was unknown.
Hospital records in Frankfurt covered 52 patients aged 18 years or younger from 2005 to 2023. A total of 31 patients arrived with bleeding at first care. Only one score part, a vein bulge near the tangle, stayed linked to bleeding after full adjustment. The full score sorted risk poorly in children by standard tests. The authors advise against direct use of the adult score for child patients.
Catalog record
| CREATOR | Sepide Kashefiolasl, Luciana Porto, Karsten Lachner, Michael Merker, Roland Schrewe, Susanne Schubert-Bast, Fee Keil, Vincent Prinz, Tobias Finger, Marcus Czabanka |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32250 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |