Serum CXCL10 as a potential biomarker for lupus nephritis and disease activity: evidence from an Egyptian cohort
Fatma Mohammed Badr, Dalia Mohamed Gamal, Ghada Maged Mohsen, Mohammed Abd El Monem Teama · 2026
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Description
Egyptian lupus patients provided the setting for a 2026 biomarker evaluation carried out under Fatma Mohammed Badr. The marker is CXCL10, a signal protein linked to lupus activity. Lupus nephritis is a serious kidney problem in people with systemic lupus.
The cross-sectional study enrolled 100 patients at Ain Shams University Hospital. Half had kidney disease and half did not. Blood CXCL10 was higher in the kidney group. Levels also rose with protein in urine, kidney strain, and disease activity scores. Levels fell as kidney filtration and protective blood proteins rose. The authors present CXCL10 as a candidate marker needing more testing.
Catalog record
| CREATOR | Fatma Mohammed Badr, Dalia Mohamed Gamal, Ghada Maged Mohsen, Mohammed Abd El Monem Teama |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64122 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |