Delayed‐Onset Hepatocellular Liver Injury Associated With Nitrofurantoin and Herbal Supplement Use: A Case Report With Multiple Potential Exposures

Edwin Mendoza, Manas Pustake, Jeffrey Annabi, Joshua Torres, Joanna Mendez, Lakshmi Kattamuri, Benjamin Williams, Abhizith Deoker · 2026

Read Delayed‐Onset Hepatocellular Liver Injury Associated With Nitrofurantoin and Herbal Supplement Use: A Case Report With Multiple Potential Exposures by Edwin Mendoza, Manas Pustake, Jeffrey Annabi, Joshua Torres, Joanna Mendez, Lakshmi Kattamuri, Benjamin Williams, Abhizith Deoker (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13282457.txt.

Description

Edwin Mendoza and co-authors describe a 2026 case of delayed liver injury in a woman exposed to two possible liver toxins at once. Nitrofurantoin is a first-line antibiotic for urinary infections that rarely causes severe liver damage. Their patient was a fifty-seven-year-old woman with fatty liver disease who developed sudden yellowing of the skin after a short antibiotic course, while also taking a commercial weight-loss supplement.

Blood tests showed strong liver cell damage, and autoimmune markers were positive, muddying the diagnosis. A liver biopsy showed non-specific inflammation favouring drug injury over autoimmune hepatitis. All suspect substances were stopped, and she received an intravenous antidote-style drug, N-acetylcysteine, urgently, though its benefit in this setting is unproven. The authors argue clinicians should weigh combined exposures when several liver-damaging substances are in play.

Catalog record

CREATOREdwin Mendoza, Manas Pustake, Jeffrey Annabi, Joshua Torres, Joanna Mendez, Lakshmi Kattamuri, Benjamin Williams, Abhizith Deoker
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE22616
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13282457

Browse the full library · About the Tower of Babel