Treatment of HER2-Positive Brain Metastasis from Cervical Cancer Using Multimodal Therapy Including Pyrotinib: A Case Report
Yuanping Chen, Ting Wen, Xinglin Wen, Zhihua Lai · 2026
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Description
Yuanping Chen and colleagues published a 2026 case report on cervical cancer that spread to the brain. Spread to the brain is rare in this cancer and the outlook is grim. The woman had an advanced cancer of mixed cell type. After drug and radiation care, a single lump appeared in her brain. Surgeons removed it, and tests showed the tumor was rich in a growth switch called HER2. That switch can be targeted by drugs.
After surgery she got focused radiation plus two drugs. One drug blocks the HER2 switch, and the other is a chemo pill. The cancer vanished on scans, a full response. Side effects stayed manageable. She stayed free of new growth for close to twenty-nine months from the brain surgery. The authors say the case hints HER2 drugs deserve study in this rare spread pattern.
Catalog record
| CREATOR | Yuanping Chen, Ting Wen, Xinglin Wen, Zhihua Lai |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17435 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |