Low systolic blood pressure increases risk of allergic rhinitis: Evidence from a bidirectional Mendelian randomization study accounting for smoking environment
Zhu Mao, Qingqing Xu, Yuting Huo, Yunliang Liu · 2026
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Description
Zhu Mao and colleagues used gene data to test a link between blood pressure and hay fever in a 2026 study. Hay fever, or allergic rhinitis, makes the nose run and itch with dust or pollen. Genes can act as a natural test, since they are set before habits form. The team checked the link in both directions with several math methods. They used more than four hundred gene markers tied to the top blood pressure number.
All methods agreed on one direction. People whose genes pointed to lower top pressure had a slightly higher risk of hay fever. The rise was small but steady across methods. The flip test found no sign that hay fever genes move blood pressure. The authors say low pressure itself may open the door to hay fever, a claim that needs more work.
Catalog record
| CREATOR | Zhu Mao, Qingqing Xu, Yuting Huo, Yunliang Liu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25948 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |