Revisiting the potential of upconversion nanoparticles in biomedical applications: Advances and emerging perspectives

Faezeh Ghorbanizamani, Hichem Moulahoum, David John Dmonte, Kalim Deshmukh · 2026

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Description

Faezeh Ghorbanizamani and colleagues give a 2026 review of upconversion nanoparticles in biomedicine. Upconversion nanoparticles turn near infrared light in higher energy light out. That trick lets probes read deep tissue with low background noise and high light stability. Clear edges over conventional probes made them a growing platform. The review takes a design view, linking particle structure to biomedical performance via synthesis, light physics and nano engineering.

Application domains span imaging, sensing and therapy delivery. New directions push the particles past passive imaging toward active, programmable systems. Key challenges persist across the field. Brightness under safe excitation stays low, and body behaviour can be hard to predict. Safe clearance from the body and reproducible builds also lag. The authors map how rational design of shells and surfaces can close those gaps.

Catalog record

CREATORFaezeh Ghorbanizamani, Hichem Moulahoum, David John Dmonte, Kalim Deshmukh
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE249719
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13280412

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