Real-world outcomes of bispecific antibody therapy after chimeric antigen receptor T-cell therapy in follicular lymphoma
John Sharp, Subodh Bhatta, Jennifer J Huang, Colin J Thomas, Omar Elghawy, Lindsey Fitzgerald, Daniel Reef, Andinet Teferra, Timothy J Voorhees, Supriya Gupta, Natalie S Grover, Stefan K Barta, Mazyar Shadman, Narendranath Epperla · 2026
Read Real-world outcomes of bispecific antibody therapy after chimeric antigen receptor T-cell therapy in follicular lymphoma by John Sharp, Subodh Bhatta, Jennifer J Huang, Colin J Thomas, Omar Elghawy, Lindsey Fitzgerald, Daniel Reef, Andinet Teferra, Timothy J Voorhees, Supriya Gupta, Natalie S Grover, Stefan K Barta, Mazyar Shadman, Narendranath Epperla (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13279774.txt.
Description
John Sharp and colleagues report a 2026 letter on bispecific antibody care after CAR T cell care in follicular lymphoma. Follicular lymphoma is the second most common non Hodgkin lymphoma, with about fourteen thousand new United States cases a year. First care can give long calm spells, yet up to half of patients need many care lines. The letter gives real world results for one sequence.
Eighteen patients got a bispecific antibody, a dual target immune drug, after CAR T care failed. Most got mosunetuzumab, and the rest got epcoritamab. Median past care lines were five. Overall response rate was sixty one percent, with full response in thirty nine percent. Best response came at a median near two and a half months. Prior CAR T response in the same group was seventy two percent. Later line immune care can still work after cell care.
Catalog record
| CREATOR | John Sharp, Subodh Bhatta, Jennifer J Huang, Colin J Thomas, Omar Elghawy, Lindsey Fitzgerald, Daniel Reef, Andinet Teferra, Timothy J Voorhees, Supriya Gupta, Natalie S Grover, Stefan K Barta, Mazyar Shadman, Narendranath Epperla |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17411 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |