Clinical dosimetry and efficacy of LED photobiomodulation for chronic lower-limb wound healing: a systematic review of randomized trials

Mariana Bezerra Miranda, Ana Carolina Silva Barros, Ana Vitoria Lima de Paula, Rayana Fontenele Alves, Rebeca Barbosa da Rocha, Vinicius Saura Cardoso · 2026

Read Clinical dosimetry and efficacy of LED photobiomodulation for chronic lower-limb wound healing: a systematic review of randomized trials by Mariana Bezerra Miranda, Ana Carolina Silva Barros, Ana Vitoria Lima de Paula, Rayana Fontenele Alves, Rebeca Barbosa da Rocha, Vinicius Saura Cardoso (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13279567.txt.

Description

Mariana Bezerra Miranda and colleagues give a 2026 systematic review of LED light care for chronic leg wounds. Long lasting leg wounds heal slowly and return often, at high cost. LED photobiomodulation uses low light to nudge tissue repair, with no cuts and low cost. Proof from trials was mixed, so the team pooled randomized trials, the strongest trial type.

Six trials met the bar, with searches in four databases to May 2026. Light colours spanned red to near infrared, and doses spanned a wide range. Most trials hinted at gains: smaller wound area, better wound bed and more blood flow, most in diabetic foot ulcers. One trial at the highest dose showed no gain. Dose may have a sweet spot, so set dose rules are the next step.

Catalog record

CREATORMariana Bezerra Miranda, Ana Carolina Silva Barros, Ana Vitoria Lima de Paula, Rayana Fontenele Alves, Rebeca Barbosa da Rocha, Vinicius Saura Cardoso
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44242
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13279567

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