The impact of antinuclear antibodies and complement levels in the prognosis of pregnant women within the antiphospholipid syndrome spectrum
Sara Garcia Bravo, Víctor M. Martínez-Taboada, Sara del Barrio-Longarela, Ana Merino, Alejandra Comins-Boo, Marcos López-Hoyos, José L. Hernández · 2026
Read The impact of antinuclear antibodies and complement levels in the prognosis of pregnant women within the antiphospholipid syndrome spectrum by Sara Garcia Bravo, Víctor M. Martínez-Taboada, Sara del Barrio-Longarela, Ana Merino, Alejandra Comins-Boo, Marcos López-Hoyos, José L. Hernández (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13279313.txt.
Description
Sara Garcia Bravo and colleagues published a 2026 study of whether two extra blood markers worsen pregnancy outlook in women within the antiphospholipid syndrome spectrum. The syndrome is an autoimmune condition tied to clots and pregnancy complications, but many patients fall short of full classification criteria. The authors studied 285 women with related obstetric problems, grouped as full syndrome, non-criteria, or seronegative cases, and tested them for antinuclear antibodies and low complement.
About 22 percent of the women tested positive for antinuclear antibodies, and they had fewer pregnancies and live births on average. Low complement, found in about 6 percent, tracked with more preeclampsia and early miscarriage, especially in the non-criteria group. Both abnormalities were also tied to greater use of antimalarial treatment during pregnancy. The authors suggest these markers flag a higher-risk subgroup that may need closer monitoring and stronger therapy, even when the classic label does not fully apply.
Catalog record
| CREATOR | Sara Garcia Bravo, Víctor M. Martínez-Taboada, Sara del Barrio-Longarela, Ana Merino, Alejandra Comins-Boo, Marcos López-Hoyos, José L. Hernández |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |