High SOX17 expression is correlated with favorable prognosis and CD8(+) TILs expression in patients with pancreatic cancer after curative resection
Jun Yu, Yuan Pan, Yi Chen, Zhihui Shu, Lin Ma, Bin Wu, Jingdong Li, Jianshui Li, Chuan Lan · 2026
Read High SOX17 expression is correlated with favorable prognosis and CD8(+) TILs expression in patients with pancreatic cancer after curative resection by Jun Yu, Yuan Pan, Yi Chen, Zhihui Shu, Lin Ma, Bin Wu, Jingdong Li, Jianshui Li, Chuan Lan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13279027.txt.
Description
Jun Yu and colleagues report a 2026 study of pancreatic cancer, a fast and deadly cancer of the pancreas gland. They look at a gene switch called SOX17 and ask if its level links to patient outcome after surgery to remove the tumour. They also ask how it links to immune cells inside the tumour.
Data from cell and bulk gene reads showed high SOX17 went with longer life after surgery. High levels also went with more CD8 T cells, a type of immune cell that kills sick cells. High levels went with fewer scar like support cells tied to poor outcome. The authors name SOX17 a helpful sign for outcome and a clue for new care paths.
Catalog record
| CREATOR | Jun Yu, Yuan Pan, Yi Chen, Zhihui Shu, Lin Ma, Bin Wu, Jingdong Li, Jianshui Li, Chuan Lan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36178 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |