Re: “Antropoli A et al. Perilesional fundus autofluorescence patterns are not static: longitudinal transitions in geographic atrophy and association with disease progression”
Marc Biarnés · 2026
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Description
Marc Biarnés wrote in 2026 about imaging patterns around geographic atrophy, the advanced dry form of macular degeneration. A study had followed 106 eyes for a median three years and found the autofluorescence pattern around the atrophy changed in 22 percent. That hints the patterns may be passing snapshots of disease progress rather than fixed signatures of a subtype.
Biarnés reopens older data. In a landmark natural history study, one test said pattern and atrophy size were unrelated, while an equally valid test gives a value just under the usual significance line, flipping the verdict. Later work tied most of the pattern's effect on growth to the starting size of the atrophy. The letter counsels caution in reading these patterns.
Catalog record
| CREATOR | Marc Biarnés |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 4 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |