Polymorphous low-grade neuroepithelial tumor of the young: a case report
Haitao Wu, Youyuan Chen, Peng Sun, Wenshuai Deng · 2026
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Description
Haitao Wu and colleagues published a 2026 case report of a rare brain tumor called polymorphous low-grade neuroepithelial tumor of the young, or PLNTY. Their patient was a 30-year-old man whose drug-resistant epilepsy had lasted six years and grown from facial twitching into mixed seizure types. Scans showed an oval abnormal area in his left temporal pole that early imaging mistook for a benign blood-vessel malformation.
After surgeons removed the lesion, pathology confirmed a low-grade growth with thin-walled vessel clusters and calcium deposits. Its proliferation index was only 1 percent, a marker of very slow growth. Staining showed diffuse CD34 and testing found a BRAF gene change without markers of aggressive cancer. The man recovered well and stayed seizure-free. The report shows why tissue and molecular testing matter when imaging alone misleads.
Catalog record
| CREATOR | Haitao Wu, Youyuan Chen, Peng Sun, Wenshuai Deng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 18 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |