Association between leptin gene polymorphisms and hematological metabolic parameters in obese Saudi adults
Lamiaa Hamad Al-Jamea, Alexander Woodman, Rehab Yusuf Al-Ansari, Fatimah Salem Alayidh, Khalid Khalaf Alharbi, Nayef Saleh Al Ahmadi, Rashid Al-Jawair, Ibrahim Sahin, Shouq Saleh AlGhamdi, Emad Johar Al Johar, Jenifer Vecina Quiambao, Abdel Halim Deifalla, Yousef Mohammed Hawsawi · 2026
Read Association between leptin gene polymorphisms and hematological metabolic parameters in obese Saudi adults by Lamiaa Hamad Al-Jamea, Alexander Woodman, Rehab Yusuf Al-Ansari, Fatimah Salem Alayidh, Khalid Khalaf Alharbi, Nayef Saleh Al Ahmadi, Rashid Al-Jawair, Ibrahim Sahin, Shouq Saleh AlGhamdi, Emad Johar Al Johar, Jenifer Vecina Quiambao, Abdel Halim Deifalla, Yousef Mohammed Hawsawi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13278879.txt.
Description
Lamiaa Hamad Al-Jamea and a large team study leptin gene variants and blood measures in obese Saudi adults, in a 2026 paper. Saudi Arabia carries one of the region's heaviest obesity burdens. Leptin is a hormone made by fat tissue that helps regulate appetite and weight.
Two hundred two adults took part, split between obese and non-obese groups, with full blood profiling for both. Obese participants showed higher white cell and platelet counts, with lower red cell measures that deepened across obesity classes. Sequencing found two leptin gene variants of interest. One variant roughly doubled obesity risk odds and tracked with higher white cell counts. The other appeared only in obese participants, in a small share.
Catalog record
| CREATOR | Lamiaa Hamad Al-Jamea, Alexander Woodman, Rehab Yusuf Al-Ansari, Fatimah Salem Alayidh, Khalid Khalaf Alharbi, Nayef Saleh Al Ahmadi, Rashid Al-Jawair, Ibrahim Sahin, Shouq Saleh AlGhamdi, Emad Johar Al Johar, Jenifer Vecina Quiambao, Abdel Halim Deifalla, Yousef Mohammed Hawsawi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |