Evolutionary inference reveals global natural histories and predicted pathways of antimicrobial resistance in Klebsiella pneumoniae
Olav N. L. Aga, Sabrina J. Moyo, Joel Manyahi, Upendo Kibwana, Iren H. Löhr, Nina Langeland, Bjørn Blomberg, Iain G. Johnston, Melissa Vazquez Hernandez, Melissa Vazquez Hernandez, Melissa Vazquez Hernandez, Melissa Vazquez Hernandez · 2026
Read Evolutionary inference reveals global natural histories and predicted pathways of antimicrobial resistance in Klebsiella pneumoniae by Olav N. L. Aga, Sabrina J. Moyo, Joel Manyahi, Upendo Kibwana, Iren H. Löhr, Nina Langeland, Bjørn Blomberg, Iain G. Johnston, Melissa Vazquez Hernandez, Melissa Vazquez Hernandez, Melissa Vazquez Hernandez, Melissa Vazquez Hernandez (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13278573.txt.
Description
Olav N L Aga leads a 2026 study that maps how drug resistance evolves in Klebsiella pneumoniae, a bacterium that causes many hospital infections. Resistance is a growing global burden, and predicting its paths could guide policy. The team used resistance features predicted from about forty-seven thousand bacterial genomes across 102 countries and a sampling method that infers likely evolutionary routes.
Some resistance behaviors were consistent worldwide, while resistance to two key drug classes varied by country. Those differences tracked with regional groupings and drug use policy. Newly sequenced African data across several decades matched the roadmap's predictions. Linking resistance forecasts to policy and social factors could strengthen responses, the authors hope.
Catalog record
| CREATOR | Olav N. L. Aga, Sabrina J. Moyo, Joel Manyahi, Upendo Kibwana, Iren H. Löhr, Nina Langeland, Bjørn Blomberg, Iain G. Johnston, Melissa Vazquez Hernandez, Melissa Vazquez Hernandez, Melissa Vazquez Hernandez, Melissa Vazquez Hernandez |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 88159 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |