High-resolution whole-brain magnetic resonance spectroscopic imaging in youth at risk for psychosis

Edgar Céléreau, Federico Lucchetti, Yasser Alemán-Gómez, Daniella Dwir, Martine Cleusix, Jean-Baptiste Ledoux, Raoul Jenni, Caroline Conchon, Meritxell Bach Cuadra, Zoé Schilliger, Alessandra Solida, Marco Armando, Kerstin Jessica Plessen, Patric Hagmann, Philippe Conus, Antoine Klauser, Paul Klauser · 2026

Read High-resolution whole-brain magnetic resonance spectroscopic imaging in youth at risk for psychosis by Edgar Céléreau, Federico Lucchetti, Yasser Alemán-Gómez, Daniella Dwir, Martine Cleusix, Jean-Baptiste Ledoux, Raoul Jenni, Caroline Conchon, Meritxell Bach Cuadra, Zoé Schilliger, Alessandra Solida, Marco Armando, Kerstin Jessica Plessen, Patric Hagmann, Philippe Conus, Antoine Klauser, Paul Klauser (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13277781.txt.

Description

Edgar Céléreau leads a 2026 brain imaging study of young people at risk for psychosis, a loss of contact with reality seen in disorders such as schizophrenia. A new scan method maps several brain chemicals across the whole brain at high detail. The team built a processing pipeline, a set of steps that cleans and aligns the maps, and tested it in two groups.

Chemical patterns matched well between the two samples and scanning sites, showing the method is stable. At-risk youth showed higher levels of one nerve-health chemical in frontal gray matter than controls. A subgroup also showed widespread rises in another chemical. Standard structure and wiring scans found no group differences, hinting the chemical maps may detect earlier change.

Catalog record

CREATOREdgar Céléreau, Federico Lucchetti, Yasser Alemán-Gómez, Daniella Dwir, Martine Cleusix, Jean-Baptiste Ledoux, Raoul Jenni, Caroline Conchon, Meritxell Bach Cuadra, Zoé Schilliger, Alessandra Solida, Marco Armando, Kerstin Jessica Plessen, Patric Hagmann, Philippe Conus, Antoine Klauser, Paul Klauser
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE62923
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13277781

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