Tailored implementation of multidomain intervention to prevent cognitive impairment in community-dwelling older adults (Timi-Cog): A study protocol for a hybrid type 2 trial effectiveness-implementation study

Zishuo Huang, Changmiao Shi, Erxu Xue, Gonghang Qiu, Yurong Jing, Ziyi Wang, Xinhua Ao, Dong (Roman) Xu, Ying Wang · 2026

Read Tailored implementation of multidomain intervention to prevent cognitive impairment in community-dwelling older adults (Timi-Cog): A study protocol for a hybrid type 2 trial effectiveness-implementation study by Zishuo Huang, Changmiao Shi, Erxu Xue, Gonghang Qiu, Yurong Jing, Ziyi Wang, Xinhua Ao, Dong (Roman) Xu, Ying Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13277494.txt.

Description

Zishuo Huang leads a 2026 study protocol for a trial to prevent memory and thinking decline in older adults living in the community in China. Combined programs that cover heart risks, brain training, activity, and diet show promise, but scaling them is hard. The protocol, for a trial across thirteen districts of Changxing County, has no results yet.

The planned trial will enroll 1,170 older adults and 273 community health workers in three groups. Support bundles include staff training, teamwork networks, and an AI-enabled phone mini-program. Outcomes on reach, health, and upkeep will be tracked over eighteen months. The design aims to judge both whether the program works and whether it can be delivered well.

Catalog record

CREATORZishuo Huang, Changmiao Shi, Erxu Xue, Gonghang Qiu, Yurong Jing, Ziyi Wang, Xinhua Ao, Dong (Roman) Xu, Ying Wang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE88977
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13277494

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