Centromeric tandem repeats expansions in plateau zokor enhance chromosome stability for high-altitude adaptation
Zhen-Long Wang, Lu-Ye Shi, Xiu-Yun Liu, Xiao-Qing Yao, Meng-Yang Li, Qiang-Hui Wang, Hao Wu, Hui-Sheng Gong, Liu-Yang Fu, Gang Chang, Li-Xin Wei, Wen-Hui Nie, Wei-Ting Su, Bo Zhao, Tao Zhang, Peng Shi · 2026
Read Centromeric tandem repeats expansions in plateau zokor enhance chromosome stability for high-altitude adaptation by Zhen-Long Wang, Lu-Ye Shi, Xiu-Yun Liu, Xiao-Qing Yao, Meng-Yang Li, Qiang-Hui Wang, Hao Wu, Hui-Sheng Gong, Liu-Yang Fu, Gang Chang, Li-Xin Wei, Wen-Hui Nie, Wei-Ting Su, Bo Zhao, Tao Zhang, Peng Shi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13276996.txt.
Description
Zhen-Long Wang leads a 2026 genome study of the plateau zokor, a burrowing rodent that lives high on the Qinghai-Tibet Plateau. The team built full genome maps for four zokor species that live at different heights. They focused on repeated DNA stretches that are often left out of genome work.
The plateau species had a larger genome, driven by growth of one repeated stretch found near centromeres, the parts that help chromosomes split evenly. Removing that repeat in cells harmed chromosome sorting, above all in low-oxygen conditions like those at altitude. The findings suggest the repeat helps guard the genome in thin air, linking junk-like DNA to survival.
Catalog record
| CREATOR | Zhen-Long Wang, Lu-Ye Shi, Xiu-Yun Liu, Xiao-Qing Yao, Meng-Yang Li, Qiang-Hui Wang, Hao Wu, Hui-Sheng Gong, Liu-Yang Fu, Gang Chang, Li-Xin Wei, Wen-Hui Nie, Wei-Ting Su, Bo Zhao, Tao Zhang, Peng Shi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64246 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |