Key hub genes and pathways associated with HCV-related hepatocellular carcinoma as potential diagnostic biomarkers
Elham Karimi, Niloufar Sadat Kalaki, Mahnaz Shavandi, Fargol Mahlouji, Abed El Hasan Haidar, Aria Abedi Asl, Fahimeh Safarnezhad Tameshkel, Farhad Zamani, Mohammad Hadi Karbalaie Niya · 2026
Read Key hub genes and pathways associated with HCV-related hepatocellular carcinoma as potential diagnostic biomarkers by Elham Karimi, Niloufar Sadat Kalaki, Mahnaz Shavandi, Fargol Mahlouji, Abed El Hasan Haidar, Aria Abedi Asl, Fahimeh Safarnezhad Tameshkel, Farhad Zamani, Mohammad Hadi Karbalaie Niya (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13276315.txt.
Description
Elham Karimi and co-authors report a 2026 journal article hunting for gene markers of liver cancer tied to hepatitis C infection. This cancer, hepatocellular carcinoma, kills many patients because it is found late. Reliable early markers could change that.
Working from two public gene datasets, the team found four hundred twenty-one genes whose activity differed in tumors. Network analysis narrowed these to eighty hub genes. The changed genes clustered in metabolic pathways and in structures that carry material out of cells. A separate database check confirmed four genes whose levels clearly split tumor from normal tissue. All four help control cell division. The authors propose them as candidate diagnostic markers for this cancer, to be tested in patients next.
Catalog record
| CREATOR | Elham Karimi, Niloufar Sadat Kalaki, Mahnaz Shavandi, Fargol Mahlouji, Abed El Hasan Haidar, Aria Abedi Asl, Fahimeh Safarnezhad Tameshkel, Farhad Zamani, Mohammad Hadi Karbalaie Niya |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34612 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |