Formononetin: a promising therapeutic agent targeting the gut-lung axis in acute lung injury
Wuliji Batu, Daijian Liu, Chunxiu Ren, Wenhui Bi, Junmei Wang, Yu Wang · 2026
Read Formononetin: a promising therapeutic agent targeting the gut-lung axis in acute lung injury by Wuliji Batu, Daijian Liu, Chunxiu Ren, Wenhui Bi, Junmei Wang, Yu Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13275679.txt.
Description
Wuliji Batu and colleagues report a 2026 mouse study of formononetin, a plant compound, in acute lung injury. The injury is a sudden inflammatory lung condition with few treatment options. The team asked whether the compound protects the lungs by acting through the gut-lung axis.
Mice with chemically induced lung injury received the compound, and lung plus gut tissues were examined closely. Treatment reduced tissue damage and lowered inflammatory signals in both organs. Gut microbe analysis linked the benefit with shifts in Parabacteroides, a bacterial genus. Chemical profiling pointed to bile acid handling and ABC transporter pathways, which the authors flag for follow-up work.
Catalog record
| CREATOR | Wuliji Batu, Daijian Liu, Chunxiu Ren, Wenhui Bi, Junmei Wang, Yu Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |