The gut-brain axis in Alzheimer’s disease: early detection, microbial metabolites, mechanisms, and therapeutic opportunities
Chenyu Liu, Zihan Zhu, Huang Lin, William S. Bush, Robert R. Jenq, Fabio Cominelli, Jagan A. Pillai, Jonathan L. Haines, Xiongwei Zhu, Rong Xu, Scott M. Williams, Feixiong Cheng, Liangliang Zhang · 2026
Read The gut-brain axis in Alzheimer’s disease: early detection, microbial metabolites, mechanisms, and therapeutic opportunities by Chenyu Liu, Zihan Zhu, Huang Lin, William S. Bush, Robert R. Jenq, Fabio Cominelli, Jagan A. Pillai, Jonathan L. Haines, Xiongwei Zhu, Rong Xu, Scott M. Williams, Feixiong Cheng, Liangliang Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13275447.txt.
Description
Chenyu Liu and colleagues present a 2026 review of the gut-brain axis in Alzheimer disease. No current drug is proven to change the course of this common cause of dementia. The review asks whether gut microbes and their chemical products offer earlier clues or new treatment routes.
The authors focus on human studies from the past five years. Gut imbalance appears in patients and may begin before memory symptoms show. Bacteria and their products may act through nerves, blood, and immune signals to affect inflammation and brain proteins. The authors call for long-term studies that combine many data types and handle diet and other confounders with care.
Catalog record
| CREATOR | Chenyu Liu, Zihan Zhu, Huang Lin, William S. Bush, Robert R. Jenq, Fabio Cominelli, Jagan A. Pillai, Jonathan L. Haines, Xiongwei Zhu, Rong Xu, Scott M. Williams, Feixiong Cheng, Liangliang Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 92 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |