Divergent effects of oral health and genetic risk: competing risks of dementia and mortality
Ruotong Liu, Xiang Qi, Yunrui Liu, Huabin Luo, Zhijing Xu, Bei Wu, Michelle Putnam · 2026
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Description
Ruotong Liu and co-authors study how tooth loss and genetic risk together steer dementia and death in old age. Their 2026 paper follows nearly ten thousand dementia-free Americans aged sixty-seven and over, using survey data linked to Medicare claims. Genetic risk came from a polygenic score for Alzheimer's disease.
Tooth loss alone did not predict dementia after full adjustment. High genetic risk did raise dementia odds, but that link weakened among people who had lost all their teeth. The same pairing raised death risk instead, suggesting many died before dementia could be recorded. The authors warn that competing risks can distort genetic studies in aging groups.
Catalog record
| CREATOR | Ruotong Liu, Xiang Qi, Yunrui Liu, Huabin Luo, Zhijing Xu, Bei Wu, Michelle Putnam |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |