The physiologic power of fluid circulation and implications for fluid therapy

William Muir · 2026

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Description

William Muir reviewed the physiology of body fluid circulation and what it means for fluid therapy in a 2026 article. Water is the body's main substance and its universal solvent, and many overlapping systems keep its balance within a narrow band. Giving intravenous fluid can rescue failing circulation, yet the same fluid given wrongly does harm.

Muir explains how healthy animals tolerate and recover from large fluid swings if balance returns before tissues starve. Poorly judged fluids instead cause imbalance, swelling, slow healing, and worse outcomes, especially in patients who cannot handle more volume. Newer readings of circulation and fluid movement, including volume kinetics, guide safer practice. Choice, dose, and timing should fit the species, the disease, and the state of the small vessels.

Catalog record

CREATORWilliam Muir
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE77 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13274250

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