Multimodality imaging characterization of Perugini scintigraphic grades in transthyretin amyloid cardiomyopathy: a single-center experience
Paulius Bucius, Evelina Zarambaite, Kornelija Lusaite, Matas Streckis, Arnas Karuzas, Jurgita Plisiene, Gintare Sakalyte, Tomas Lapinskas, Donatas Vajauskas, Antanas Jankauskas, Egle Ereminiene · 2026
Read Multimodality imaging characterization of Perugini scintigraphic grades in transthyretin amyloid cardiomyopathy: a single-center experience by Paulius Bucius, Evelina Zarambaite, Kornelija Lusaite, Matas Streckis, Arnas Karuzas, Jurgita Plisiene, Gintare Sakalyte, Tomas Lapinskas, Donatas Vajauskas, Antanas Jankauskas, Egle Ereminiene (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13274190.txt.
Description
Paulius Bucius and colleagues report a 2026 journal article comparing heart scan grades in a disease where abnormal protein clogs the heart muscle. Transthyretin amyloid cardiomyopathy is now often diagnosed with a bone tracer scan instead of biopsy, graded by how strongly the heart lights up. Whether the two positive grades differ in severity was uncertain.
Reviewing 302 scans done from 2018 to 2025, the team found fifty-three confirmed cases, only eight at grade two and forty-five at grade three. Grade three patients walked shorter distances in six minutes and had thicker heart walls, weaker pumping, and higher troponin, a damage marker. Scan grade tracked closely with heart muscle mass on MRI.
Catalog record
| CREATOR | Paulius Bucius, Evelina Zarambaite, Kornelija Lusaite, Matas Streckis, Arnas Karuzas, Jurgita Plisiene, Gintare Sakalyte, Tomas Lapinskas, Donatas Vajauskas, Antanas Jankauskas, Egle Ereminiene |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34651 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |