Resting state brain connectivity of pain and fatigue is affected by performance of a fatiguing attention task in patients with chronic pain

Nils Berginström, Marika C. Möller, Anna Holmqvist, Monika Löfgren, Britt-Marie Stålnacke, Love Engström Nordin · 2026

Read Resting state brain connectivity of pain and fatigue is affected by performance of a fatiguing attention task in patients with chronic pain by Nils Berginström, Marika C. Möller, Anna Holmqvist, Monika Löfgren, Britt-Marie Stålnacke, Love Engström Nordin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13273879.txt.

Description

Berginström and colleagues examine brain links tied to pain and fatigue in chronic pain patients. Their 2026 journal article uses resting state fMRI scans. Participants also performed a twenty-minute attention task designed to tire them.

The study included 24 women with chronic pain. It also included 22 healthy controls of similar age. Patients reported more fatigue and pain than controls. Before the task, the groups differed in several brain networks. The default mode network showed the clearest gaps. After the task, most group gaps could no longer be seen. Only links between the basal ganglia and frontal areas remained distinct. Pain-linked gaps showed up mainly before the task. Fatigue-linked gaps showed up after the task. The authors suggest fatigue can crowd out pain in brain activity.

Catalog record

CREATORNils Berginström, Marika C. Möller, Anna Holmqvist, Monika Löfgren, Britt-Marie Stålnacke, Love Engström Nordin
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45550
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13273879

Browse the full library · About the Tower of Babel