Diagnosing and Managing Paradoxical Deep Vein Thrombosis in a Patient With Congenital Afibrinogenemia
Altamash Jawadi, Malik Alqawasmi, Mahmoud Abdelsamia, Hemza Assed, Mohammad Adawee, Mohammad Badawy, Xuan Thuy T Nguyen, Andres E Mindiola Romero, Allison Burnett, Ala Ebaid · 2026
Read Diagnosing and Managing Paradoxical Deep Vein Thrombosis in a Patient With Congenital Afibrinogenemia by Altamash Jawadi, Malik Alqawasmi, Mahmoud Abdelsamia, Hemza Assed, Mohammad Adawee, Mohammad Badawy, Xuan Thuy T Nguyen, Andres E Mindiola Romero, Allison Burnett, Ala Ebaid (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13273846.txt.
Description
Jawadi and colleagues report a 2026 case of deep vein thrombosis in a young man with congenital afibrinogenemia. That rare disorder means the blood lacks fibrinogen, a protein needed for clotting. Oddly, the condition can also raise clot risk.
The man arrived with extensive clots in his leg veins. His fibrinogen level was undetectable. His D-dimer was deceptively low, since that test depends on fibrin. Doctors balanced blood thinners with fibrinogen replacement. Genetic testing confirmed a homozygous change in the FGB gene. After three months of therapy he had improved. Some chronic clot changes remained. The authors urge tailored treatment for such patients.
Catalog record
| CREATOR | Altamash Jawadi, Malik Alqawasmi, Mahmoud Abdelsamia, Hemza Assed, Mohammad Adawee, Mohammad Badawy, Xuan Thuy T Nguyen, Andres E Mindiola Romero, Allison Burnett, Ala Ebaid |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 11892 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |