Design and rationale of the WE-CARE-HF-CMR trial: Cardiorenal care on wheels for asymptomatic heart failure patients (NCT07185100)

Jeffrey Ji-Peng Li, Gisela Thiede, Collin Götze, Vasileios Exarchos, Cyrill Meuwly, Stefanie Maria Werhahn, Rebecca Elisabeth Beyer, Maximilian Leo Müller, Tamar Bigvava, Christian Stehning, Bjoern Andrew Remppis, Johannes Wieditz, Stefan Sack, Tobias Heer, Michael Sroka, Eike Nagel, Allison G. Hays · 2026

Read Design and rationale of the WE-CARE-HF-CMR trial: Cardiorenal care on wheels for asymptomatic heart failure patients (NCT07185100) by Jeffrey Ji-Peng Li, Gisela Thiede, Collin Götze, Vasileios Exarchos, Cyrill Meuwly, Stefanie Maria Werhahn, Rebecca Elisabeth Beyer, Maximilian Leo Müller, Tamar Bigvava, Christian Stehning, Bjoern Andrew Remppis, Johannes Wieditz, Stefan Sack, Tobias Heer, Michael Sroka, Eike Nagel, Allison G. Hays (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13273793.txt.

Description

A large team of cardiologists lays out a trial hunting silent heart failure in city populations in a paper from 2026. The catalog creator list is truncated, so the trial is described with team framing. Standard measures miss early disease, but a strain measure from heart imaging catches it. A prior rural study using mobile MRI trucks found nearly a quarter of screened adults had this silent stage. The new trial recruits asymptomatic adults with risk factors in five German cities.

Participants get history checks, lab tests, heart MRI with strain analysis, and quality-of-life surveys. Both fixed and mobile scanners are used. The main goal is the share of city dwellers with silent disease. Follow-up explores how their hearts change.

Catalog record

CREATORJeffrey Ji-Peng Li, Gisela Thiede, Collin Götze, Vasileios Exarchos, Cyrill Meuwly, Stefanie Maria Werhahn, Rebecca Elisabeth Beyer, Maximilian Leo Müller, Tamar Bigvava, Christian Stehning, Bjoern Andrew Remppis, Johannes Wieditz, Stefan Sack, Tobias Heer, Michael Sroka, Eike Nagel, Allison G. Hays
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13273793

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