Preliminary clinical and electrophysiological findings of NAc/ALIC deep brain stimulation strategy for treatment-resistant depression
Wei Zhang, Botao Xiong, Yukun Kang, Yuan Gao, Ruiqing Yang, Qiang Wang, Wei Wang · 2026
Read Preliminary clinical and electrophysiological findings of NAc/ALIC deep brain stimulation strategy for treatment-resistant depression by Wei Zhang, Botao Xiong, Yukun Kang, Yuan Gao, Ruiqing Yang, Qiang Wang, Wei Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13273470.txt.
Description
Wei Zhang and co-authors reported early findings on dual target deep brain stimulation for treatment-resistant depression in a 2026 study. Many patients do not respond to drugs or talk therapy, and stimulation offers another route. Their approach targeted two sites at once: the nucleus accumbens and a capsule pathway nearby.
In a small patient group, symptoms eased and thinking performance improved after stimulation. Brain recordings taken during treatment showed that improvement tracked with stronger gamma rhythms at the target site. Theta rhythm power also rose in frontal and limbic regions. The authors frame the work as preliminary, offering a first map of how the therapy may act and which signals might guide tuning for each patient.
Catalog record
| CREATOR | Wei Zhang, Botao Xiong, Yukun Kang, Yuan Gao, Ruiqing Yang, Qiang Wang, Wei Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |