Capillary Electrophoresis With Amperometric Detection for Neurotransmitter Analysis: Principles, Electrode Materials, Methodologies, and Applications
Petr Kubáň, Jiří Volánek, Nguyen Thi Thu Trang, Tran Dai Lam · 2026
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Description
Kubáň and three co-authors wrote a 2026 review of a lab method that sorts brain chemicals in a thin tube and reads them by electric current. The method handles tiny samples with great care, suiting scarce neurotransmitters. This is the first review devoted to monoamine transmitters and their kin in living systems. It covers how detection works, where sensors sit, and how high voltage is kept apart.
The review compares sensor materials, from carbon fiber and glassy carbon to noble metals, diamond, and modified designs. It weighs noise, sensitivity, fouling, and ease of use for each. Phosphate buffers dominate, while another buffer family reaches the lowest detection limits. Uses run from urine and blood to brain tissue and single cells. The authors also flag fouling and interface limits as barriers to clinical use.
Catalog record
| CREATOR | Petr Kubáň, Jiří Volánek, Nguyen Thi Thu Trang, Tran Dai Lam |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 119 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |