Arabidopsis YEATS domain proteins facilitate DNA double-strand break repair via homology-directed pathways
Neeraja Vegesna, Laura Bouza-Morcillo, Clara Bourbousse, Yasaman Jami-Alahmadi, En Li, Maherun Nisa, Ana Marie S. Palanca, James A. Wohlschlegel, Julie A. Law · 2026
Read Arabidopsis YEATS domain proteins facilitate DNA double-strand break repair via homology-directed pathways by Neeraja Vegesna, Laura Bouza-Morcillo, Clara Bourbousse, Yasaman Jami-Alahmadi, En Li, Maherun Nisa, Ana Marie S. Palanca, James A. Wohlschlegel, Julie A. Law (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13273319.txt.
Description
Neeraja Vegesna and colleagues identified two chromatin reader proteins that help repair broken DNA in plants in a 2026 study. Repair happens inside chromatin, the packed form of DNA, yet plant proteins that link the two were poorly known. The team worked in Arabidopsis thaliana, a model plant.
The readers, named YAF9A and YAF9B, proved critical for fixing double strand breaks through homology directed repair, which copies information from a matching DNA stretch. Each reader connects to a distinct chromatin remodeling complex, the machines that loosen or shift DNA packaging. The reading domain of YAF9B was required for its protective role. The authors say these findings close a gap in how plants coordinate repair with chromatin state.
Catalog record
| CREATOR | Neeraja Vegesna, Laura Bouza-Morcillo, Clara Bourbousse, Yasaman Jami-Alahmadi, En Li, Maherun Nisa, Ana Marie S. Palanca, James A. Wohlschlegel, Julie A. Law |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |