Salivary Biomarkers for Diagnosis and Monitoring of Thyroid Diseases: A Systematic Review of Current Evidence
Chandrasekaran Krithika, Chitathoor Sridhar, Srijanani Santhanakrishnan, Jaideep Mahendra, Leena Sankari, Tharanikumar Sivakumar · 2026
Read Salivary Biomarkers for Diagnosis and Monitoring of Thyroid Diseases: A Systematic Review of Current Evidence by Chandrasekaran Krithika, Chitathoor Sridhar, Srijanani Santhanakrishnan, Jaideep Mahendra, Leena Sankari, Tharanikumar Sivakumar (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13272866.txt.
Description
Chandrasekaran Krithika leads a 2026 systematic review of whether saliva can be used to diagnose and monitor thyroid disease. Saliva testing is non-invasive, so it appeals as an alternative to blood draws. The team searched five databases up to May 2025 for human studies linking saliva markers to thyroid conditions.
From 35 records found, nine studies were included for detailed synthesis by two independent reviewers. Markers that showed promise included a thyroid hormone, amino acids, metabolic profiles, sugar patterns on proteins, microbes, and thyroid antibodies. However, studies varied widely in design and lab methods, so firm conclusions are not yet possible. Better designed clinical studies are needed to validate saliva screening.
Catalog record
| CREATOR | Chandrasekaran Krithika, Chitathoor Sridhar, Srijanani Santhanakrishnan, Jaideep Mahendra, Leena Sankari, Tharanikumar Sivakumar |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22866 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |