Reconsidering the interpretation of dermoscopic criteria for acral lentiginous melanoma: dermoscopic features show promise, but real-world implementation faces unresolved barriers—a comment on Okwara et al.
Shiqiong Zhou, Qinghua Ke · 2026
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Description
Shiqiong Zhou and Qinghua Ke wrote a 2026 comment on skin-scope signs for acral lentiginous melanoma, a melanoma on palms, soles, or nails. They respond to a meta-analysis that confirmed the parallel ridge pattern as a strong sign of this cancer. That pattern had 79.6 percent sensitivity and 99.4 percent specificity in the review.
The authors warn that about 20 percent of these melanomas lack that pattern, so its absence cannot rule out cancer. They also question the high specificity, since only 25 percent of benign lesions in the studies were confirmed by tissue tests. They call for future studies to record lesion site and pressure from walking or use.
Catalog record
| CREATOR | Shiqiong Zhou, Qinghua Ke |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 6463 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |