Manganese: biology, physiology and role in disease

Zhidan Xia, Xinran Li, Rui Liu, Karin Tuschl, Junxia Min, Fudi Wang · 2026

Read Manganese: biology, physiology and role in disease by Zhidan Xia, Xinran Li, Rui Liu, Karin Tuschl, Junxia Min, Fudi Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13272668.txt.

Description

Zhidan Xia leads a 2026 review arguing that manganese, a trace metal, plays a far larger role in health than its old image as a mere enzyme helper. The review gathers recent work on how the body handles manganese and what happens when that balance fails. It covers roles in fat handling, immune signaling, and cell balance.

Too much or too little manganese is linked to metabolic syndrome, Parkinson-like brain harm, liver and heart disease, and immune problems, the authors say. Faults in metal transporter genes can drive some cases. Future work they outline includes diet changes, targeted transporter therapies, and clearer exposure limits to protect public health.

Catalog record

CREATORZhidan Xia, Xinran Li, Rui Liu, Karin Tuschl, Junxia Min, Fudi Wang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE97108
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13272668

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