Trichosporon inkin empyema and fungaemia following bilateral lung transplantation: diagnostic and treatment challenges
David M. Mannion, Assumpta Killarney, Nicola Ronan, Peter Riddell, Breda Lynch, Margaret M. Hannan · 2026
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Description
David M. Mannion and co-authors reported a difficult fungal infection after lung transplantation in a 2026 case report. A 60 year old man worsened six weeks after receiving two new lungs. Testing found a yeast called Trichosporon inkin in both his chest fluid and his blood.
Doctors confirmed the infection with biochemical tests and fungal DNA sequencing. Treatment combined drainage of the infected chest fluid, guided by imaging, with the antifungal drug voriconazole. Blood levels of the drug were checked and adjusted to reach a safe target. The authors say this is the first reported case with both sites infected at once. They stress molecular testing and firm source control in transplant care.
Catalog record
| CREATOR | David M. Mannion, Assumpta Killarney, Nicola Ronan, Peter Riddell, Breda Lynch, Margaret M. Hannan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |