Shelf-life extension of lettuce using cell-penetrating peptide-peptide nucleic acid conjugates targeting Sphingomonaspaucimobilis
Su-jin Yum, Seon Yeong Yu, Seung Min Kim, Seockmo Ku, Hee Gon Jeong · 2026
Read Shelf-life extension of lettuce using cell-penetrating peptide-peptide nucleic acid conjugates targeting Sphingomonaspaucimobilis by Su-jin Yum, Seon Yeong Yu, Seung Min Kim, Seockmo Ku, Hee Gon Jeong (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13272553.txt.
Description
Su-jin Yum and colleagues tested a targeted antimicrobial treatment to extend lettuce shelf life in a 2026 study. A bacterium called Sphingomonas paucimobilis spoils plant foods and can also harm people. Normal preservation cannot easily remove one species without disturbing the rest.
Their approach uses short nucleic acid strands that block key genes in the target bacterium, joined to peptides that carry them into cells. The best carrier killed the bacterium at low doses by silencing genes it needs to copy DNA and make proteins. Mismatched strands had no effect, which showed precise targeting. Spraying the treatment on lettuce at a low dose cut discoloration and slowed bacterial growth. The authors propose such tools for safer fresh produce.
Catalog record
| CREATOR | Su-jin Yum, Seon Yeong Yu, Seung Min Kim, Seockmo Ku, Hee Gon Jeong |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |