Genomic and transcriptomic evaluation of primary and recurrent luminal B-like breast cancer
L. Li, G. Yin, X. Liu, J. Zhang, C. Zhou, P. Song, L. Zhao, W. Zhou, S. Huang, Z. Yu · 2026
Read Genomic and transcriptomic evaluation of primary and recurrent luminal B-like breast cancer by L. Li, G. Yin, X. Liu, J. Zhang, C. Zhou, P. Song, L. Zhao, W. Zhou, S. Huang, Z. Yu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13272503.txt.
Description
L. Li and co-authors compared primary and recurrent luminal B-like breast cancer in a 2026 genomic study. This subtype makes up a large share of breast cancers and returns more often than the luminal A form. The team wanted to learn which changes drive recurrence and which might be treated.
They sequenced DNA from a panel of cancer genes and also read RNA in samples from 15 patients. Most mutations and copy changes were already present in the first tumor and stayed through recurrence. TP53 and PIK3CA were altered most often, while some changes appeared only later. Recurrent tumors showed more T cells, and greater unevenness in the first tumor linked to shorter time without return.
Catalog record
| CREATOR | L. Li, G. Yin, X. Liu, J. Zhang, C. Zhou, P. Song, L. Zhao, W. Zhou, S. Huang, Z. Yu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |