Establishment of a blocking enzyme-linked immunosorbent assay based on tandem expression of dominant antigenic epitopes of the nucleocapsid protein from attenuated and virulent peste des petits ruminants virus
Kaiyu Zhu, Xiaolong Gao, Lina Tong, Xinchao Du, Yun Chen, Jinxin Xie, Shanhui Ren · 2026
Read Establishment of a blocking enzyme-linked immunosorbent assay based on tandem expression of dominant antigenic epitopes of the nucleocapsid protein from attenuated and virulent peste des petits ruminants virus by Kaiyu Zhu, Xiaolong Gao, Lina Tong, Xinchao Du, Yun Chen, Jinxin Xie, Shanhui Ren (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13272494.txt.
Description
Kaiyu Zhu and co-authors built a new antibody test in 2026 for peste des petits ruminants, a contagious virus disease of goats and sheep. Fast and reliable testing helps farms judge vaccine response and control outbreaks. Their test targets antibodies against the virus nucleocapsid protein.
The team joined key protein fragments from weak and strong virus strains and made the combined protein in bacteria. They then tuned a blocking enzyme test that uses this protein and a labeled antibody. The test detected positive serum diluted tenfold and gave steady results across repeats. It did not react to several other pathogens. On 100 farm samples it agreed with a commercial kit in most cases.
Catalog record
| CREATOR | Kaiyu Zhu, Xiaolong Gao, Lina Tong, Xinchao Du, Yun Chen, Jinxin Xie, Shanhui Ren |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |