Research progress on HIV-1 structural proteins and antiviral therapies
Huihan Wang, Jinsong Yuan, Hong Wang · 2026
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Description
Huihan Wang and coauthors review in 2026 progress on the structural proteins of HIV-1 and the drugs that target them. The virus's Gag, Pol, and Env proteins run its life cycle, from assembly to entry into new cells. Blocking their functions remains a main engine of anti-AIDS drug development.
The narrative review covers recent inhibitor advances against each protein family and the mechanisms those drugs exploit. Resistance and delivery problems that limit current therapy receive attention as well. The authors close with design strategies for the next generation of antivirals, aiming at durable control of a virus that still infects millions worldwide.
Catalog record
| CREATOR | Huihan Wang, Jinsong Yuan, Hong Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |