Cannabinoid receptor expression profiling in lymphocyte subsets reveals clinically relevant immune patterns in SLE
Angie M. Rosero, Lady J. Rios-Serna, Carlos A. Cañas · 2026
Read Cannabinoid receptor expression profiling in lymphocyte subsets reveals clinically relevant immune patterns in SLE by Angie M. Rosero, Lady J. Rios-Serna, Carlos A. Cañas (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13272394.txt.
Description
Angie M Rosero and coauthors measure in 2026 cannabinoid receptors on immune cells of patients with lupus, hunting for patterns tied to disease activity. The two receptors, CB1R and CB2R, tune immune behavior, yet their distribution across lupus lymphocyte types was uncharted. Blood cells from thirty-five patients and thirty-five healthy controls were compared by flow cytometry.
Patients showed higher CB2R and lower CB1R than controls across several cell subsets. CB1R levels tracked closely with disease activity, and patients in remission looked much like healthy controls. Certain B-cell CB2R patterns separated active disease from remission well, suggesting both a biomarker and a drug target.
Catalog record
| CREATOR | Angie M. Rosero, Lady J. Rios-Serna, Carlos A. Cañas |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |