Review on biological active metabolites of Astragali radix and its mechanisms in treating allergic respiratory diseases

Zeyun Wang, Jie Cui, Shaoyan Zhang, Yu Wang, Lei Qiu, Zifeng Ma, Huimin Shen, Zhenhui Lu, Cui Li · 2026

Read Review on biological active metabolites of Astragali radix and its mechanisms in treating allergic respiratory diseases by Zeyun Wang, Jie Cui, Shaoyan Zhang, Yu Wang, Lei Qiu, Zifeng Ma, Huimin Shen, Zhenhui Lu, Cui Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13272347.txt.

Description

Zeyun Wang and coauthors review in 2026 the active compounds of Astragali Radix, a classic Chinese medicinal root, and how they act against allergic airway diseases. Asthma, allergic rhinitis, and related conditions are rising worldwide. The root's sugars, saponins, and flavonoids carry most of its studied effects.

Two compounds, a saponin called AS-IV and the polysaccharide fraction, dominate the research record. Reported actions include calming inflammation, rebalancing immune cell types, and slowing airway wall remodeling and scarring. The review treats the allergic airway diseases as one spectrum and ties each compound class to the signaling pathways it touches.

Catalog record

CREATORZeyun Wang, Jie Cui, Shaoyan Zhang, Yu Wang, Lei Qiu, Zifeng Ma, Huimin Shen, Zhenhui Lu, Cui Li
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE122 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13272347

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