Multi-Class Pharmaceutical Profiling Along an Urbanization Gradient in a Tropical Megacity River: Evidence for Cumulative Loading and Limited Attenuation
Wulan Koagouw, Riyana Subandi, Rina Adriany, Richard J Hazell · 2026
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Description
Wulan Koagouw is lead author of a 2026 journal article profiling drug pollution along Jakarta's Ciliwung River, in Indonesia. Drug residues threaten water life and human health. Yet tropical city rivers are far less studied than temperate ones. So the team sampled along a gradient of urbanisation to test whether pollution builds up downstream.
They analysed 53 compounds at eight sites and detected thirteen. These spanned antibiotics, painkillers, heart drugs, and scan contrast agents. Combined levels rose clearly downstream. The nerve drug gabapentin showed the strongest build-up. Eleven compounds increased steadily, signalling cumulative loading with little breakdown. Local spikes for two drugs suggested point sources such as health facility discharge. Gabapentin is proposed as a watch-list indicator.
Catalog record
| CREATOR | Wulan Koagouw, Riyana Subandi, Rina Adriany, Richard J Hazell |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25438 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |