Characteristics, treatment regimens, and outcomes of patients with true extramedullary multiple myeloma: a real-world monocentric analysis

Marie Harzer, Nils Gross-Fengels, Fede Melzer, Isabel Molwitz, Ricardo Kosch, Maximilian Al-Bazaz, Jule Artzenroth, Leon Cords, Leandra Bartke, Abdulaziz Kamili, Winfried Alsdorf, Carsten Bokemeyer, Katja Weisel, Lisa B. Leypoldt, Christoph Schaefers · 2026

Read Characteristics, treatment regimens, and outcomes of patients with true extramedullary multiple myeloma: a real-world monocentric analysis by Marie Harzer, Nils Gross-Fengels, Fede Melzer, Isabel Molwitz, Ricardo Kosch, Maximilian Al-Bazaz, Jule Artzenroth, Leon Cords, Leandra Bartke, Abdulaziz Kamili, Winfried Alsdorf, Carsten Bokemeyer, Katja Weisel, Lisa B. Leypoldt, Christoph Schaefers (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13272244.txt.

Description

Marie Harzer is lead author of a 2026 real-world analysis of true extramedullary multiple myeloma, a form of the bone marrow cancer where tumours grow in soft tissue away from bone. This subtype stays aggressive with poor outcomes despite major treatment advances, and no shared management consensus or dedicated trials exist.

The single-centre review covered 86 patients with scan-confirmed disease, 19 present at first diagnosis and 67 appearing at relapse. Treatment was highly varied, with over fifty distinct regimens. Median survival from the extramedullary occurrence was 28 months for new cases and 21 for relapse cases. Disease in the central nervous system, lungs, or behind the abdomen trended worst, while lymph node disease lasted significantly longer.

Catalog record

CREATORMarie Harzer, Nils Gross-Fengels, Fede Melzer, Isabel Molwitz, Ricardo Kosch, Maximilian Al-Bazaz, Jule Artzenroth, Leon Cords, Leandra Bartke, Abdulaziz Kamili, Winfried Alsdorf, Carsten Bokemeyer, Katja Weisel, Lisa B. Leypoldt, Christoph Schaefers
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE65996
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13272244

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