Exploring the relationship between retinal damage and cognition in multiple sclerosis: a cross-sectional OCT-MRI study
Riccardo Maria Borgo, Manuela Altieri, Alessandro Pasquale De Rosa, Rocco Capuano, Alvino Bisecco, Fabrizio Esposito, Alessandro Tessitore, Alessandro d’Ambrosio, Antonio Gallo · 2026
Read Exploring the relationship between retinal damage and cognition in multiple sclerosis: a cross-sectional OCT-MRI study by Riccardo Maria Borgo, Manuela Altieri, Alessandro Pasquale De Rosa, Rocco Capuano, Alvino Bisecco, Fabrizio Esposito, Alessandro Tessitore, Alessandro d’Ambrosio, Antonio Gallo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13272231.txt.
Description
Riccardo Maria Borgo is lead author of a 2026 cross-sectional study linking retinal damage to cognition in multiple sclerosis. In that disease, immune attacks on nerves cause brain shrinkage and disabling thinking problems. Eye scans called OCT measure retinal layer thickness quickly and cheaply. They offer a possible window on brain degeneration.
One hundred people with multiple sclerosis had thinking tests, brain MRI scans, and retinal scans of several layers. Thinner retinal layers tracked with smaller brain volumes and lower cognitive performance. One layer, the ganglion cell layer, showed the strongest links, especially with processing speed and executive function, and was the only retinal predictor left in statistical models. Patients with impaired cognition had thinner ganglion and nerve fibre layers.
Catalog record
| CREATOR | Riccardo Maria Borgo, Manuela Altieri, Alessandro Pasquale De Rosa, Rocco Capuano, Alvino Bisecco, Fabrizio Esposito, Alessandro Tessitore, Alessandro d’Ambrosio, Antonio Gallo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40376 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |