Elevated TFR1 is associated with inflammatory burden and ferroptosis in ulcerative colitis
Xiaotong He, Jieru Ji, Lingmei Feng, Guoyu Chen, Yao Yao · 2026
Read Elevated TFR1 is associated with inflammatory burden and ferroptosis in ulcerative colitis by Xiaotong He, Jieru Ji, Lingmei Feng, Guoyu Chen, Yao Yao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13272019.txt.
Description
Xiaotong He and coauthors measure in 2026 a blood iron-handling protein in people with ulcerative colitis and relate it to inflammation and a form of iron-driven cell death. Transferrin receptor 1 pulls iron into cells, and its role in this bowel disease was undefined. Iron balance, oxidative stress, and inflammation all shift in active colitis.
Blood from 83 patients with active disease held clearly higher receptor levels than samples from 80 healthy controls, rising further with disease severity. Levels tracked with standard inflammation markers, clotting measures, and a lipid damage marker of the cell death process. The authors propose the protein as a candidate severity marker.
Catalog record
| CREATOR | Xiaotong He, Jieru Ji, Lingmei Feng, Guoyu Chen, Yao Yao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |