Immunopathogenesis of antibody-mediated rejection in liver transplantation
Bo Luo, Mengyue Wang, Guoyu Chen, Wang Li, Yuanyi Mang, Shengning Zhang · 2026
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Description
Bo Luo and colleagues review in 2026 how antibody-driven rejection injures transplanted livers. This rejection type is rarer in liver transplants than in kidney or heart grafts, yet it can cause lasting damage and graft loss. Diagnosis is hard because blood, tissue, and symptom signs often stay incomplete or overlap.
The review separates evidence gathered in liver grafts from ideas borrowed from other organs and lab models. Donor-specific antibodies, complement activity, and small-vessel inflammation interact with the liver's unusual tolerance to antibody attack. The authors propose a practical frame that joins antibody tests, tissue signs, and graft function to guide treatment choices.
Catalog record
| CREATOR | Bo Luo, Mengyue Wang, Guoyu Chen, Wang Li, Yuanyi Mang, Shengning Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |