Distinct pathophysiological mechanisms of Heterometrus laoticus and Lychas mucronatus scorpion venoms on cardiovascular and renal functions
Narongsak Chaiyabutr, Lawan Chanhome, Panithi Laoungbua, Taksa Vasaruchapong, Orawan Khow, Onrapak Reamtong, Asada Leelahavanichkul, Visith Sitprija · 2026
Read Distinct pathophysiological mechanisms of Heterometrus laoticus and Lychas mucronatus scorpion venoms on cardiovascular and renal functions by Narongsak Chaiyabutr, Lawan Chanhome, Panithi Laoungbua, Taksa Vasaruchapong, Orawan Khow, Onrapak Reamtong, Asada Leelahavanichkul, Visith Sitprija (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13271812.txt.
Description
Narongsak Chaiyabutr is lead author of a 2026 journal article comparing two Southeast Asian scorpion venoms, from Heterometrus laoticus and Lychas mucronatus, on the heart, blood vessels, and kidneys. Both species are widespread, but their venom effects were poorly characterised because human deaths are uncommon.
In anaesthetised rabbits given intravenous venom, the first species caused a quick, brief drop in blood pressure followed by a mild long low phase. The second caused a brief drop, then a significant rise, then a terminal fall. Kidney changes followed the blood pressure swings. Chemical profiling showed the second venom is rich in nerve toxins that tighten vessels, while the first carries more of an enzyme linked to vessel widening. Treatment should be species-specific, they conclude.
Catalog record
| CREATOR | Narongsak Chaiyabutr, Lawan Chanhome, Panithi Laoungbua, Taksa Vasaruchapong, Orawan Khow, Onrapak Reamtong, Asada Leelahavanichkul, Visith Sitprija |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62883 |
| LICENSE | https://creativecommons.org/publicdomain/zero/1.0 |
| RIGHTS | CC0 |
| SOURCE | Europe PMC |