Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang · 2026
Read Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing by Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13271646.txt.
Description
Sha Yu and seven co-authors review a fast route to antibiotic susceptibility answers. Watch how the metabolism of bacteria flinches under a drug, in place of waiting for colonies to grow. Resistance spreads faster than tests, and genotype tests cannot be trusted to predict real-world resistance. Metabolic readouts can return a verdict in hours or minutes, with no need for cells to split.
The review first explains how antibiotics disturb the metabolism of bacteria and how resistance shows up in metabolic terms. Biomarkers are then sorted by their roots: nutrient uptake, respiration, metabolic rewiring, and enzyme activity. Challenges to roll-out close the survey, from shared standards to clinical checks. The team place this kind of testing between slow culture and gene panels one cannot rely on.
Catalog record
| CREATOR | Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 95 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |