CXCL13-expressing CD4+ T cells coordinate the lymphocytes triad to promote the anti-tumor immunity in NSCLC
Danping Liu, Jiajun Luo, Wei Guo, Junrui Ma, Xiaobao Yang, Yihan Xia, Pu Li, Dakang Xu, Zhidong Gu · 2026
Read CXCL13-expressing CD4+ T cells coordinate the lymphocytes triad to promote the anti-tumor immunity in NSCLC by Danping Liu, Jiajun Luo, Wei Guo, Junrui Ma, Xiaobao Yang, Yihan Xia, Pu Li, Dakang Xu, Zhidong Gu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13271355.txt.
Description
Danping Liu and coauthors report in 2026 on a helper T cell group that seems to organize other immune cells inside lung tumors. These CD4 cells make a signal called CXCL13, which attracts B cells that carry its matching receptor. The question was whether that pairing helps killer T cells attack non-small-cell lung cancer.
Combining single-cell gene data with tissue staining, the team found the three cell types sitting together in tumors. Patients whose tumors held this three-cell grouping tended to fare better. The pattern points to a local immune team that strengthens tumor attack, and it may help doctors judge which patients carry a more active defense.
Catalog record
| CREATOR | Danping Liu, Jiajun Luo, Wei Guo, Junrui Ma, Xiaobao Yang, Yihan Xia, Pu Li, Dakang Xu, Zhidong Gu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |