The protease code of the bacterial gut microbiota: ecological regulation, barrier disruption, and rewiring host defense and signaling
Ulrich Eckhard, Juan Sebastián Ramírez-Larrota, Eva Estevan-Morió, F. Xavier Gomis-Rüth · 2026
Read The protease code of the bacterial gut microbiota: ecological regulation, barrier disruption, and rewiring host defense and signaling by Ulrich Eckhard, Juan Sebastián Ramírez-Larrota, Eva Estevan-Morió, F. Xavier Gomis-Rüth (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13271334.txt.
Description
Ulrich Eckhard is lead author of a 2026 review titled around the protease code of gut bacteria. Proteases are enzymes that cut proteins, and gut microbes use them not just for digestion but as precise signals that shape the microbial community and its contact with the human host.
The review first covers how proteases remodel the protein scaffolding of microbial biofilms and jam chemical signals bacteria use to coordinate. It then details attacks on host barriers, from enzymes that thin the protective mucus layer to named toxins that cut the joints between gut lining cells. Finally, it shows proteases hijacking host signalling, splitting antibody defences and switching on inflammation receptors.
Catalog record
| CREATOR | Ulrich Eckhard, Juan Sebastián Ramírez-Larrota, Eva Estevan-Morió, F. Xavier Gomis-Rüth |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 78011 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |